Categories: Nasal Ketamine

How Effective Is Nasal Esketamine for Depression?

Nasal Esketamine spray is used in conjunction with medication taken by mouth to manage depression. It is only supposed to be used in a health care setting. This should be under the supervision of a health care provider. You will not be able to use it at home.

Nasal Esketamine spray

Before taking the medicine, a person should weigh the risk of taking it against the good it will do. This is a decision a patient should make with the doctor. It can cause side effects, some of which can be serious. Here is a breakdown of how it should be used and its benefits.

Benefits

Nasal Esketamine is a good treatment option for depression. Studies have shown that when combined with an oral antidepressant, it can help decrease depression symptoms. It can be recommended when other treatments have not been beneficial. It has helped many patients with treatment-resistant depression. These are mainly patients who have struggled with depression and tried two or more antidepressants without adequate relief.

Proper use

A person needs to take a dose of this medicine under a medical professional’s supervision. It is often taken twice a week during the first four weeks. It then has to be taken once weekly. After this period, a person is supposed to take it once a week or once every two weeks.

A health care provider will let the patient know how often it should be used. Some people taking it get nausea and vomiting. A patient should not consume anything for at least two hours before taking the medicine. Avoiding drinking liquids within 30 minutes before taking it is also ideal.

A patient will be monitored closely for at least two hours after taking it. This is necessary because the medicine can cause side effects like severe drowsiness and dissociation. A health care provider will decide when a patient is ready to leave the health care setting. A patient may have to be driven home after taking the medicine. A person should not operate machinery, drive or do anything that requires an individual to be completely alert. Taking part in these activities is not advisable until the next day following a restful sleep.

Other options

Aside from taking the medicine and oral antidepressant, there might be other things a person can do. A patient should ask the health care provider about what else can be done to manage depression. If some form of talk therapy has been included in the treatment plan, a person should stick to it. Sometimes, lifestyle changes can be beneficial. These include exercise, better sleep and dietary changes. They can also help to reduce the symptoms of depression.

Takeaway

Nasal Esketamine has been proven to be effective for depression treatment. A health care provider may recommend it if it can help improve your symptoms. However, you should be aware of the risks and benefits of the medicine before making any decisions. To find out whether Nasal Esketamine spray is right for you and to learn more about the possible side effects, talk to your psychiatrist.

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Don A. DuBose, M.D., M.S.

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