How Is Nasal Esketamine Used to Treat Depression?

Many health care providers recommend Nasal Esketamine spray for the management of treatment-resistant depression (TRD). This depression is resistant to other treatments. You might have TRD if you have been treated for depression but your symptoms have not improved. But you should not lose hope. There are many other approaches that your health care provider may suggest that can be beneficial.

Nasal Esketamine for depression

Many people feel sad or hopeless from time to time. This is not unusual and it is a natural part of life. But for people suffering from depression, these feelings can become not only intense but also long-lasting. This can affect a person’s qualify of life. It can lead to problems at home, work and school.

Depression is often treated with a combination of antidepressant medication and some form of therapy. For some, antidepressants provide adequate relief on their own. While antidepressants help many people, they do not improve symptoms for some people with depression. Some patients only notice a partial improvement in depression symptoms.

How Nasal Esketamine is used

Esketamine is a nasal spray that is used with an oral antidepressant to treat depression. A person has to take a dose of the medicine under the supervision of a health care provider in a medical facility. Esketamine works by changing the activity of particular natural substances in a person’s brain. It comes as a solution or liquid to spray into the nose.

Every nasal spray device provides two sprays, one for each nostril. A health care provider will determine how many devices a patient should use depending on the dose. Esketamine usually causes nausea and vomiting. A person should not eat for at least two hours before using it. Not drinking liquid at least 30 minutes before using the medicine is also recommended.

Other ways to manage depression

There are other things people can do to manage depression while using esketamine nasal spray. Sometimes, some form of therapy may be included in a patient’s treatment plan. Lifestyle changes can also help people with depression. Exercise, better sleep and dietary changes can improve depression symptoms.

Who should avoid taking it?

A person who is allergic to esketamine or ketamine should not use this medicine. It is not recommended for a person with a blood vessel disorder that affects the brain, heart, stomach, chest or arms and legs. It is also not suitable for a person with a history of aneurysm or bleeding in the brain. The same goes for a person who has an abnormal connection between the arteries and veins. This condition is called an arteriovenous malformation.

Takeaway

Nasal Esketamine can be prescribed to people with depression who have tried and received no benefit from two or more antidepressant treatments. More people are using it because of its benefits. But this medicine is not recommended for everyone. People with certain conditions are not supposed to use it. A person should ask a health care provider if it is a good option. If you have any questions about this medicine, get in touch with your psychiatrist.

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